Disease relevance of Mcrs1

• Cycloheximide alone (3 mg/kg body weight) produced microspherules, whereas in combination with a dose of 1 or 2 mg of urethan per g body weight it partially prevented or potentiated, respectively, the microspherule production [1].

High impact information on Mcrs1

• Influence of phenobarbital on microspherule production by urethan in mouse hepatocyte nucleoli [2].

Analytical, diagnostic and therapeutic context of Mcrs1

• We have used these antibodies and immune cat serum in immunoprecipitation and Western blotting experiments and have identified novel proteins in FCV-infected cells which we term P78, P41, P35 and P29 [3].
• The same viral suspension was also injected sub-retinally into rhodopsin-knockout rho (-/-) mice either at P18 or P78, and retinas were analyzed by immunohistochemistry and PNA lectin histochemistry two weeks later [4].

References