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Gene Review

PELO  -  pelota homolog (Drosophila)

Homo sapiens

Synonyms: CGI-17, PRO1770, Protein pelota homolog
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High impact information on PELO

  • As Pelo is highly conserved from Drosophila to mammals, it may also be involved in the regulation of adult stem cell self-renewal in mammals, including humans [1].
  • Molecular cloning, expression and chromosome location of the human pelota gene PELO [2].

Analytical, diagnostic and therapeutic context of PELO


  1. Pelota controls self-renewal of germline stem cells by repressing a Bam-independent differentiation pathway. Xi, R., Doan, C., Liu, D., Xie, T. Development (2005) [Pubmed]
  2. Molecular cloning, expression and chromosome location of the human pelota gene PELO. Shamsadin, R., Adham, I.M., von Beust, G., Engel, W. Cytogenet. Cell Genet. (2000) [Pubmed]
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