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Gene Review:

kif11 - kinesin family member 11

Xenopus (Silurana) tropicalis

Synonyms: Cos2, Costal2, eg5, hksp, knsl1, ...

Satinover, D.L. et al., Sawin, K.E. et al., Vernos, I. et al.

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High impact information on kif11

Xklp1, a chromosomal Xenopus kinesin-like protein essential for spindle organization and chromosome positioning [1].
In addition, interactions with targeting protein for Xenopus kinesin-like protein 2 (TPX2) allosterically activate Aurora-A [2].
Eg5, a member of the bimC subfamily of kinesin-like microtubule motor proteins, localizes to spindle microtubules in mitosis but not to interphase microtubules [3].

References

Xklp1, a chromosomal Xenopus kinesin-like protein essential for spindle organization and chromosome positioning. Vernos, I., Raats, J., Hirano, T., Heasman, J., Karsenti, E., Wylie, C. Cell (1995) [Pubmed]
Activation of Aurora-A kinase by protein phosphatase inhibitor-2, a bifunctional signaling protein. Satinover, D.L., Leach, C.A., Stukenberg, P.T., Brautigan, D.L. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
Mutations in the kinesin-like protein Eg5 disrupting localization to the mitotic spindle. Sawin, K.E., Mitchison, T.J. Proc. Natl. Acad. Sci. U.S.A. (1995) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

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Klp61F	Drosophila melanogaster
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