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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

CASC1  -  cancer susceptibility candidate 1

Homo sapiens

Synonyms: Cancer susceptibility candidate gene 1 protein, FLJ10921, LAS1, Lung adenoma susceptibility 1-like protein, PPP1R54, ...
 
 
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Disease relevance of CASC1

  • These findings suggest that the LRMP V141L polymorphism can predict survival in lung ADCA and that the role of LRMP and CASC1 in human lung cancer risk may differ from that in mice [1].
  • One hundred and ten consecutive breast cancer patients hospitalised for surgery were randomised between being sent the comprehensive assessment of satisfaction with care (CASC) at 2 weeks (T(2W)) or at 3 months (T(3M)) after hospital discharge [2].
 

Psychiatry related information on CASC1

  • CONCLUSIONS: Results of present psychometric testing of the CASC forecast adequate properties [3].
 

Analytical, diagnostic and therapeutic context of CASC1

References

  1. A V141L polymorphism of the human LRMP gene is associated with survival of lung cancer patients. Manenti, G., Galbiati, F., Pettinicchio, A., Spinola, M., Piconese, S., Leoni, V.P., Conti, B., Ravagnani, F., Incarbone, M., Pastorino, U., Dragani, T.A. Carcinogenesis (2006) [Pubmed]
  2. Timing of patient satisfaction assessment: effect on questionnaire acceptability, completeness of data, reliability and variability of scores. Brédart, A., Razavi, D., Robertson, C., Brignone, S., Fonzo, D., Petit, J.Y., de Haes, J.C. Patient education and counseling. (2002) [Pubmed]
  3. A comprehensive assessment of satisfaction with care: preliminary psychometric analysis in an oncology institute in Italy. Brédart, A., Razavi, D., Robertson, C., Didier, F., Scaffidi, E., de Haes, J.C. Ann. Oncol. (1999) [Pubmed]
  4. Candidate lung tumor susceptibility genes identified through whole-genome association analyses in inbred mice. Liu, P., Wang, Y., Vikis, H., Maciag, A., Wang, D., Lu, Y., Liu, Y., You, M. Nat. Genet. (2006) [Pubmed]
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