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Nop58  -  NOP58 ribonucleoprotein

Mus musculus

Synonyms: MSSP, Nol5, Nucleolar protein 5, Nucleolar protein 58, SIK, ...
 
 
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High impact information on Nol5

  • These findings demonstrate the potential usefulness of SIK cultures as a model for studying keratinocyte responses to carcinogens activated by TCDD-induced cytochromes P450 [1].
  • Immunoblotting experiments were performed to examine the induced expression of the KID-1 and SIK proteins in PC12 cells [2].
  • As expected, Northern blots indicate that ATC1 cells expressed mRNAs for the enzymes of corticosterone metabolism CYP11B1 and CYP21A, as well as those for the proteins SIK, SRB1, StAR, CYP11A1, and AKR1B7 [3].
 

Analytical, diagnostic and therapeutic context of Nol5

  • SIK protein increases significantly at 2 hr after treatment, peaks between 4 and 6 hr, and returns to the basal level at 8 hr [2].

References

  1. 2,3,7,8-Tetrachlorodibenzo-p-dioxin sensitization of cultured human epidermal cells to carcinogenic heterocyclic amine toxicity. Walsh, A.A., deGraffenried, L.A., Rice, R.H. Carcinogenesis (1995) [Pubmed]
  2. Expression of depolarization-induced immediate early gene proteins in PC12 cells. Liu, W., Feldman, J.D., Machado, H.B., Vician, L.J., Herschman, H.R. J. Neurosci. Res. (2003) [Pubmed]
  3. ACTH and PRL sensitivity of highly differentiated cell lines obtained by adrenocortical targeted oncogenesis. Ragazzon, B., Lefrançois-Martinez, A.M., Val, P., Tournaire, C., Berger, M., Gachancard-Bouya, J.L., Bègue, R.J., Veyssière, G., Martinez, A. Endocr. Res. (2004) [Pubmed]
 
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