MeSH Review:
PC12 Cells
- Differentiation of PC12 phaeochromocytoma cells induced by v-src oncogene. Alemà, S., Casalbore, P., Agostini, E., Tatò, F. Nature (1985)
- Rac regulates phosphorylation of the myosin-II heavy chain, actinomyosin disassembly and cell spreading. van Leeuwen, F.N., van Delft, S., Kain, H.E., van der Kammen, R.A., Collard, J.G. Nat. Cell Biol. (1999)
- The role of cAMP in nerve growth factor-promoted neurite outgrowth in PC12 cells. Richter-Landsberg, C., Jastorff, B. J. Cell Biol. (1986)
- Differential transactivation of sphingosine-1-phosphate receptors modulates NGF-induced neurite extension. Toman, R.E., Payne, S.G., Watterson, K.R., Maceyka, M., Lee, N.H., Milstien, S., Bigbee, J.W., Spiegel, S. J. Cell Biol. (2004)
- Essential role of the disulfide-bonded loop of chromogranin B for sorting to secretory granules is revealed by expression of a deletion mutant in the absence of endogenous granin synthesis. Krömer, A., Glombik, M.M., Huttner, W.B., Gerdes, H.H. J. Cell Biol. (1998)
- Secreted form of amyloid beta/A4 protein precursor (APP) binds to two distinct APP binding sites on rat B103 neuron-like cells through two different domains, but only one site is involved in neuritotropic activity. Ninomiya, H., Roch, J.M., Jin, L.W., Saitoh, T. J. Neurochem. (1994)
- Selective inhibition of the expression of signal transduction proteins by lithium in nerve growth factor-differentiated PC12 cells. Li, X., Jope, R.S. J. Neurochem. (1995)
- Modulation of amphetamine-stimulated [3H]dopamine release from rat pheochromocytoma (PC12) cells by sigma type 2 receptors. Weatherspoon, J.K., Werling, L.L. J. Pharmacol. Exp. Ther. (1999)
- Cytokines modulate the inflammatory response and change permissiveness to neuronal adhesion in injured mammalian central nervous system. Lotan, M., Solomon, A., Ben-Bassat, S., Schwartz, M. Exp. Neurol. (1994)
- SNARE complex formation is triggered by Ca2+ and drives membrane fusion. Chen, Y.A., Scales, S.J., Patel, S.M., Doung, Y.C., Scheller, R.H. Cell (1999)
- cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway. Vossler, M.R., Yao, H., York, R.D., Pan, M.G., Rim, C.S., Stork, P.J. Cell (1997)
- Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Marshall, C.J. Cell (1995)
- The syntaxin family of vesicular transport receptors. Bennett, M.K., García-Arrarás, J.E., Elferink, L.A., Peterson, K., Fleming, A.M., Hazuka, C.D., Scheller, R.H. Cell (1993)
- A role for synaptotagmin (p65) in regulated exocytosis. Elferink, L.A., Peterson, M.R., Scheller, R.H. Cell (1993)
- Two peptides derived from the nerve growth factor precursor are biologically active. Dicou, E., Pflug, B., Magazin, M., Lehy, T., Djakiew, D., Ferrara, P., Nerrière, V., Harvie, D. J. Cell Biol. (1997)
- Nerve growth factor nonresponsive pheochromocytoma cells: altered internalization results in signaling dysfunction. Eveleth, D.D., Bradshaw, R.A. J. Cell Biol. (1992)
- Affinity labeling and partial purification of nerve growth factor receptors from rat pheochromocytoma and human melanoma cells. Grob, P.M., Berlot, C.H., Bothwell, M.A. Proc. Natl. Acad. Sci. U.S.A. (1983)
- D2-Like dopamine autoreceptor activation reduces quantal size in PC12 cells. Pothos, E.N., Przedborski, S., Davila, V., Schmitz, Y., Sulzer, D. J. Neurosci. (1998)
- Regulation of bradykinin- and ATP-activated Ca(2+)-permeable channels in rat pheochromocytoma (PC12) cells. Neuhaus, R., Reber, B.F., Reuter, H. J. Neurosci. (1991)
- Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases. Thomas, S.M., DeMarco, M., D'Arcangelo, G., Halegoua, S., Brugge, J.S. Cell (1992)
- ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK. Wood, K.W., Sarnecki, C., Roberts, T.M., Blenis, J. Cell (1992)
- Rim is a putative Rab3 effector in regulating synaptic-vesicle fusion. Wang, Y., Okamoto, M., Schmitz, F., Hofmann, K., Südhof, T.C. Nature (1997)
- Phosphatidylinositol-3-OH kinase as a direct target of Ras. Rodriguez-Viciana, P., Warne, P.H., Dhand, R., Vanhaesebroeck, B., Gout, I., Fry, M.J., Waterfield, M.D., Downward, J. Nature (1994)
- A functional cyclic AMP response element plays a crucial role in neuroendocrine cell type-specific expression of the secretory granule protein chromogranin A. Wu, H., Mahata, S.K., Mahata, M., Webster, N.J., Parmer, R.J., O'Connor, D.T. J. Clin. Invest. (1995)
- Cloning of complementary DNA for GAP-43, a neuronal growth-related protein. Karns, L.R., Ng, S.C., Freeman, J.A., Fishman, M.C. Science (1987)
- Synaptophysin is sorted from endocytotic markers in neuroendocrine PC12 cells but not transfected fibroblasts. Linstedt, A.D., Kelly, R.B. Neuron (1991)
- Processing of chromogranin A by plasmin provides a novel mechanism for regulating catecholamine secretion. Parmer, R.J., Mahata, M., Gong, Y., Mahata, S.K., Jiang, Q., O'Connor, D.T., Xi, X.P., Miles, L.A. J. Clin. Invest. (2000)
- Synaptotagmin IV is necessary for the maturation of secretory granules in PC12 cells. Ahras, M., Otto, G.P., Tooze, S.A. J. Cell Biol. (2006)
- ADP ribosylation factor 1 is required for synaptic vesicle budding in PC12 cells. Faúndez, V., Horng, J.T., Kelly, R.B. J. Cell Biol. (1997)
- Clonal variants of PC12 pheochromocytoma cells with altered response to nerve growth factor. Bothwell, M.A., Schechter, A.L., Vaughn, K.M. Cell (1980)
- Black widow spider toxin-induced calcium fluxes and transmitter release in a neurosecretory cell line. Grasso, A., Alemà, S., Rufini, S., Senni, M.I. Nature (1980)
- Functional acetylcholine receptor in PC12 cells reacts with a monoclonal antibody to brain nicotinic receptors. Whiting, P.J., Schoepfer, R., Swanson, L.W., Simmons, D.M., Lindstrom, J.M. Nature (1987)
- High brain densities of the immunophilin FKBP colocalized with calcineurin. Steiner, J.P., Dawson, T.M., Fotuhi, M., Glatt, C.E., Snowman, A.M., Cohen, N., Snyder, S.H. Nature (1992)
- Neuroregulatory and neuropathological actions of the ether-phospholipid platelet-activating factor. Kornecki, E., Ehrlich, Y.H. Science (1988)
- Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras. Rosen, L.B., Ginty, D.D., Weber, M.J., Greenberg, M.E. Neuron (1994)
- The rat trkC locus encodes multiple neurogenic receptors that exhibit differential response to neurotrophin-3 in PC12 cells. Tsoulfas, P., Soppet, D., Escandon, E., Tessarollo, L., Mendoza-Ramirez, J.L., Rosenthal, A., Nikolics, K., Parada, L.F. Neuron (1993)
- Identification and characterization of novel substrates of Trk receptors in developing neurons. Qian, X., Riccio, A., Zhang, Y., Ginty, D.D. Neuron (1998)
- Small GTPase Rin induces neurite outgrowth through Rac/Cdc42 and calmodulin in PC12 cells. Hoshino, M., Nakamura, S. J. Cell Biol. (2003)
- Cellubrevin and synaptobrevins: similar subcellular localization and biochemical properties in PC12 cells. Chilcote, T.J., Galli, T., Mundigl, O., Edelmann, L., McPherson, P.S., Takei, K., De Camilli, P. J. Cell Biol. (1995)
- The Wnt-1 proto-oncogene induces changes in morphology, gene expression, and growth factor responsiveness in PC12 cells. Shackleford, G.M., Willert, K., Wang, J., Varmus, H.E. Neuron (1993)
- A protein induced by NGF in PC12 cells is stored in secretory vesicles and released through the regulated pathway. Possenti, R., Eldridge, J.D., Paterson, B.M., Grasso, A., Levi, A. EMBO J. (1989)
- ras isoprenylation is required for ras-induced but not for NGF-induced neuronal differentiation of PC12 cells. Qiu, M.S., Pitts, A.F., Winters, T.R., Green, S.H. J. Cell Biol. (1991)
- Microtubule dynamics in nerve cells: analysis using microinjection of biotinylated tubulin into PC12 cells. Okabe, S., Hirokawa, N. J. Cell Biol. (1988)
- Clusters of neural cell adhesion molecule at sites of cell-cell contact. Bloch, R.J. J. Cell Biol. (1992)