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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

NKG2D  -  NKG2D protein

Macaca mulatta

Synonyms: KLRK1, NKG2-D
 
 
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Disease relevance of NKG2D

  • Molecular and functional characterization of NKG2D, NKp80, and NKG2C triggering NK cell receptors in rhesus and cynomolgus macaques: monitoring of NK cell function during simian HIV infection [1].
 

High impact information on NKG2D

  • Both M. fascicularis and M. mulatta NK cells express NKp80, NKG2D, and NKG2C molecules, which displayed a high degree of sequence homology with their human counterpart [1].
  • In addition to quantitating NKG2A, NKG2B, NKG2C2, NKG2C and NKG2D expression, mRNA expression of transmembrane-deleted forms of these molecules was also evaluated [2].

References

  1. Molecular and functional characterization of NKG2D, NKp80, and NKG2C triggering NK cell receptors in rhesus and cynomolgus macaques: monitoring of NK cell function during simian HIV infection. Biassoni, R., Fogli, M., Cantoni, C., Costa, P., Conte, R., Koopman, G., Cafaro, A., Ensoli, B., Moretta, A., Moretta, L., De Maria, A. J. Immunol. (2005) [Pubmed]
  2. Variable NKG2 expression in the peripheral blood lymphocytes of rhesus monkeys. Labonte, M.L., Letvin, N.L. Clin. Exp. Immunol. (2004) [Pubmed]
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