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Gene Review

OVOL2  -  ovo-like zinc finger 2

Homo sapiens

Synonyms: EUROIMAGE566589, HOVO2, Transcription factor Ovo-like 2, ZNF339, Zinc finger protein 339, ...
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High impact information on OVOL2

  • These transcripts are produced by alternative promoter usage and alternative splicing and encode long and short OVOL2 protein isoforms, whose sequences differ from those previously reported [1].
  • Mouse and human OVOL2 genes are expressed in overlapping tissues including testis, where Ovol2 expression is developmentally regulated and correlates with the meiotic/postmeiotic stages of spermatogenesis [1].
  • Mouse Ovol2 maps to chromosome 2 in a region containing blind-sterile (bs), a spontaneous mutation that causes spermatogenic defects and germ cell loss [1].


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