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Gene Review:

Carm1 - coactivator-associated arginine...

Mus musculus

Synonyms: Coactivator-associated arginine methyltransferase 1, Histone-arginine methyltransferase CARM1, Prmt4, Protein arginine N-methyltransferase 4

Chen, S.L. et al., Yadav, N. et al.

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High impact information on Carm1

Specific protein methylation defects and gene expression perturbations in coactivator-associated arginine methyltransferase 1-deficient mice [1].
The coactivator-associated arginine methyltransferase is necessary for muscle differentiation: CARM1 coactivates myocyte enhancer factor-2 [2].

Associations of Carm1 with chemical compounds

SRCs have been demonstrated to recruit CARM1 (coactivator-associated arginine methyltransferase-1), a member of the S-adenosyl-l-methionine-dependent PRMT1-5 (protein-arginine N-methyltransferase-1-5) family, which catalyzes the methylation of arginine residues [2].

References

Specific protein methylation defects and gene expression perturbations in coactivator-associated arginine methyltransferase 1-deficient mice. Yadav, N., Lee, J., Kim, J., Shen, J., Hu, M.C., Aldaz, C.M., Bedford, M.T. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
The coactivator-associated arginine methyltransferase is necessary for muscle differentiation: CARM1 coactivates myocyte enhancer factor-2. Chen, S.L., Loffler, K.A., Chen, D., Stallcup, M.R., Muscat, G.E. J. Biol. Chem. (2002) [Pubmed]

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