Gene Review:
CARM1 - coactivator-associated arginine...
Homo sapiens
Synonyms:
Coactivator-associated arginine methyltransferase 1, Histone-arginine methyltransferase CARM1, PRMT4, Protein arginine N-methyltransferase 4
- Aberrant expression of CARM1, a transcriptional coactivator of androgen receptor, in the development of prostate carcinoma and androgen-independent status. Hong, H., Kao, C., Jeng, M.H., Eble, J.N., Koch, M.O., Gardner, T.A., Zhang, S., Li, L., Pan, C.X., Hu, Z., MacLennan, G.T., Cheng, L. Cancer (2004)
- Coactivator-Associated Arginine Methyltransferase 1 Enhances Transcriptional Activity of the Human T-Cell Lymphotropic Virus Type 1 Long Terminal Repeat through Direct Interaction with Tax. Jeong, S.J., Lu, H., Cho, W.K., Park, H.U., Pise-Masison, C., Brady, J.N. J. Virol. (2006)
- The Arginine Methyltransferase CARM1 Regulates the Coupling of Transcription and mRNA Processing. Cheng, D., C??t??, J., Shaaban, S., Bedford, M.T. Mol. Cell (2007)
- Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53. An, W., Kim, J., Roeder, R.G. Cell (2004)
- Histone deimination antagonizes arginine methylation. Cuthbert, G.L., Daujat, S., Snowden, A.W., Erdjument-Bromage, H., Hagiwara, T., Yamada, M., Schneider, R., Gregory, P.D., Tempst, P., Bannister, A.J., Kouzarides, T. Cell (2004)
- Regulation of transcription by a protein methyltransferase. Chen, D., Ma, H., Hong, H., Koh, S.S., Huang, S.M., Schurter, B.T., Aswad, D.W., Stallcup, M.R. Science (1999)
- A methylation-mediator complex in hormone signaling. Xu, W., Cho, H., Kadam, S., Banayo, E.M., Anderson, S., Yates, J.R., Emerson, B.M., Evans, R.M. Genes Dev. (2004)
- Control of CBP co-activating activity by arginine methylation. Chevillard-Briet, M., Trouche, D., Vandel, L. EMBO J. (2002)
- Arginine methyltransferase CARM1 is a promoter-specific regulator of NF-kappaB-dependent gene expression. Covic, M., Hassa, P.O., Saccani, S., Buerki, C., Meier, N.I., Lombardi, C., Imhof, R., Bedford, M.T., Natoli, G., Hottiger, M.O. EMBO J. (2005)
- Interplay among coactivator-associated arginine methyltransferase 1, CBP, and CIITA in IFN-gamma-inducible MHC-II gene expression. Zika, E., Fauquier, L., Vandel, L., Ting, J.P. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Loss of CARM1 results in hypomethylation of thymocyte cyclic AMP-regulated phosphoprotein and deregulated early T cell development. Kim, J., Lee, J., Yadav, N., Wu, Q., Carter, C., Richard, S., Richie, E., Bedford, M.T. J. Biol. Chem. (2004)
- Coactivator-associated arginine methyltransferase-1 enhances nuclear factor-kappaB-mediated gene transcription through methylation of histone H3 at arginine 17. Miao, F., Li, S., Chavez, V., Lanting, L., Natarajan, R. Mol. Endocrinol. (2006)
- CARM1 regulates proliferation of PC12 cells by methylating HuD. Fujiwara, T., Mori, Y., Chu, D.L., Koyama, Y., Miyata, S., Tanaka, H., Yachi, K., Kubo, T., Yoshikawa, H., Tohyama, M. Mol. Cell. Biol. (2006)
- Lipopolysaccharide-induced methylation of HuR, an mRNA-stabilizing protein, by CARM1. Coactivator-associated arginine methyltransferase. Li, H., Park, S., Kilburn, B., Jelinek, M.A., Henschen-Edman, A., Aswad, D.W., Stallcup, M.R., Laird-Offringa, I.A. J. Biol. Chem. (2002)
- Signal-dependent control of gluconeogenic key enzyme genes through coactivator-associated arginine methyltransferase 1. Krones-Herzig, A., Mesaros, A., Metzger, D., Ziegler, A., Lemke, U., Brüning, J.C., Herzig, S. J. Biol. Chem. (2006)
- The activity and stability of the transcriptional coactivator p/CIP/SRC-3 are regulated by CARM1-dependent methylation. Naeem, H., Cheng, D., Zhao, Q., Underhill, C., Tini, M., Bedford, M.T., Torchia, J. Mol. Cell. Biol. (2007)
- Hormone-dependent, CARM1-directed, arginine-specific methylation of histone H3 on a steroid-regulated promoter. Ma, H., Baumann, C.T., Li, H., Strahl, B.D., Rice, R., Jelinek, M.A., Aswad, D.W., Allis, C.D., Hager, G.L., Stallcup, M.R. Curr. Biol. (2001)
- SNF2-related CBP activator protein (SRCAP) functions as a coactivator of steroid receptor-mediated transcription through synergistic interactions with CARM-1 and GRIP-1. Monroy, M.A., Schott, N.M., Cox, L., Chen, J.D., Ruh, M., Chrivia, J.C. Mol. Endocrinol. (2003)
- Signaling within a Coactivator Complex: Methylation of SRC-3/AIB1 Is a Molecular Switch for Complex Disassembly. Feng, Q., Yi, P., Wong, J., O'malley, B.W. Mol. Cell. Biol. (2006)
- Developmentally essential protein flightless I is a nuclear receptor coactivator with actin binding activity. Lee, Y.H., Campbell, H.D., Stallcup, M.R. Mol. Cell. Biol. (2004)
- Requirement for multiple domains of the protein arginine methyltransferase CARM1 in its transcriptional coactivator function. Teyssier, C., Chen, D., Stallcup, M.R. J. Biol. Chem. (2002)