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Gene Review:

Acrv1 - acrosomal vesicle protein 1

Rattus norvegicus

Hussein, M.R. et al., Kanbara, K. et al., Yang, W.X. et al., Lewis, B. et al.

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High impact information on Acrv1

KIFC1, a C-terminal kinesin motor, first appears on membrane-bounded organelles (MBOs) in the medulla of early spermatids followed by localization to the acrosomal vesicle [1].
As cells pass from the caput to the cauda epididymis, tyrosine phosphorylation becomes confined to a narrow band at the posterior margin of the acrosomal vesicle [2].
Electron microscopic immunocytochemistry revealed that, during cap phase, GABA and GABAB1 were distributed within the whole acrosomal vesicle but not in the acrosomal granule [3].
Also, this Group showed features of an increased metabolic activity (large acrosomal vesicle, prominent Golgi, increased mitotic activity, increased complement of cytoplasmic organelles and appearance of nucleoli-like bodies) [4].

References

C-terminal kinesin motor KIFC1 participates in acrosome biogenesis and vesicle transport. Yang, W.X., Sperry, A.O. Biol. Reprod. (2003) [Pubmed]
Impact of epididymal maturation on the tyrosine phosphorylation patterns exhibited by rat spermatozoa. Lewis, B., Aitken, R.J. Biol. Reprod. (2001) [Pubmed]
Cellular localization of GABA and GABAB receptor subunit proteins during spermiogenesis in rat testis. Kanbara, K., Okamoto, K., Nomura, S., Kaneko, T., Shigemoto, R., Azuma, H., Katsuoka, Y., Watanabe, M. J. Androl. (2005) [Pubmed]
Morphological evaluation of the radioprotective effects of melatonin against X-ray-induced early and acute testis damage in Albino rats: an animal model. Hussein, M.R., Abu-Dief, E.E., Abou El-Ghait, A.T., Adly, M.A., Abdelraheem, M.H. International journal of experimental pathology. (2006) [Pubmed]

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ACRV1	Bos taurus
ACRV1	Canis lupus familiaris
ACRV1	Homo sapiens
LOC713422	Macaca mulatta
Acrv1	Mus musculus
ACRV1	Pan troglodytes

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