The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene Review

SNORD13P1  -  small nucleolar RNA, C/D box 13 pseudogene 1

Homo sapiens

Synonyms: RNU13P1, U13, U13.32A
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of RNU13P1

  • The backbone torsion angles, which partially influence the local conformation of U12 and U14 in U1 and U3-hairpins, respectively, are probably locked in the trans conformation as in the case of U13 in the U2-hairpin [1].

High impact information on RNU13P1

  • The U3, U8 and U13 snoRNA genes are transcribed independently, whereas U14-U24, as well as E3, are located within introns of protein-coding genes, most of whose functions are linked to translation [2].
  • Fractionation of HeLa cells revealed that U8 and U13, like U3, reside in the nucleolus [3].
  • U3, U8 and U13 comprise a new class of mammalian snRNPs localized in the cell nucleolus [3].
  • We propose that U3, U8 and U13 comprise a new subset of mammalian snRNPs whose roles in ribosome biogenesis are discussed [3].
  • The unassigned sheep syntenic groups U8 and U13 are provisionally assigned to sheep chromosomes 8 and 21, respectively [4].

Biological context of RNU13P1

  • Three pseudogenes for human U13 snRNA belong to class III [5].
  • These pseudogenes belong to class III because they contain dispersed mismatches when compared to the previously determined U13 RNA sequence, an adenine-rich region at the 3' end, and short imperfect repeats flanking the 5' end of the coding sequence and the 3' end of the adenine-rich region [5].

Analytical, diagnostic and therapeutic context of RNU13P1

  • Sequence analysis revealed that one of these RNAs, 136 nucleotides long, is the human U8 homolog; while the other, 105 nucleotides long, represents a novel species which we designate U13 [3].
  • METHODS: Anthropometry, maturity status, functional and sport-specific parameters were assessed in elite, sub-elite, and non-elite youth players in four age groups: U13 (n = 117), U14 (n = 136), U15 (n = 138) and U16 (n = 99) [6].


  1. Structural basis for poor uracil excision from hairpin DNA. An NMR study. Ghosh, M., Rumpal, N., Varshney, U., Chary, K.V. Eur. J. Biochem. (2002) [Pubmed]
  2. A mammalian gene with introns instead of exons generating stable RNA products. Tycowski, K.T., Shu, M.D., Steitz, J.A. Nature (1996) [Pubmed]
  3. U3, U8 and U13 comprise a new class of mammalian snRNPs localized in the cell nucleolus. Tyc, K., Steitz, J.A. EMBO J. (1989) [Pubmed]
  4. Regional assignment of conserved reference loci anchors unassigned linkage and syntenic groups to ovine chromosomes. Ansari, H.A., Pearce, P.D., Maher, D.W., Broad, T.E. Genomics (1994) [Pubmed]
  5. Three pseudogenes for human U13 snRNA belong to class III. Baserga, S.J., Yang, X.D., Steitz, J.A. Gene (1991) [Pubmed]
  6. A multidisciplinary selection model for youth soccer: the Ghent Youth Soccer Project. Vaeyens, R., Malina, R.M., Janssens, M., Van Renterghem, B., Bourgois, J., Vrijens, J., Philippaerts, R.M. British journal of sports medicine. (2006) [Pubmed]
WikiGenes - Universities