The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Gene Review

SNORD20  -  small nucleolar RNA, C/D box 20

Homo sapiens

Synonyms: RNU20, U20
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on SNORD20

  • U20 RNA contains an extended region (21 nucleotides) of perfect complementarity with a phylogenetically conserved sequence in 18S rRNA [1].
  • In mammals, U20 RNA is an 80-nucleotide-long, metabolically stable species, present at about 7 x 10(3) molecules per exponentially growing HeLa cell [1].
  • We specifically propose that residues C75, U20 and C21 form the basis of the catalytic region and are close to the cleavable phosphate [2].
  • NMR data indicate that the structure of a mutant having G20 changed to U20 is nearly identical with that of the normal sequence, suggesting that the low aminoacylation activity of this variant is not due to a substantially different conformation [3].

References

  1. U20, a novel small nucleolar RNA, is encoded in an intron of the nucleolin gene in mammals. Nicoloso, M., Caizergues-Ferrer, M., Michot, B., Azum, M.C., Bachellerie, J.P. Mol. Cell. Biol. (1994) [Pubmed]
  2. A three-dimensional model of hepatitis delta virus ribozyme based on biochemical and mutational analyses. Tanner, N.K., Schaff, S., Thill, G., Petit-Koskas, E., Crain-Denoyelle, A.M., Westhof, E. Curr. Biol. (1994) [Pubmed]
  3. Structure of an unmodified tRNA molecule. Hall, K.B., Sampson, J.R., Uhlenbeck, O.C., Redfield, A.G. Biochemistry (1989) [Pubmed]
 
WikiGenes - Universities