Gene Review:
SURF4 - surfeit 4
Homo sapiens
Synonyms:
ERV29, FLJ22993, MGC102753, SURF-4, Surfeit locus protein 4
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High impact information on SURF4
- Salt and detergent extraction procedures showed that the surf-4 protein associated tightly with the microsomal membranes [1].
- Consistent with the presence of the ER retrieval motif, the surf-4 myc protein was not detected at the plasma membrane [1].
- Primary sequence analysis predicts that the mouse surf-4 protein contains seven transmembrane domains and a double lysine endoplasmic reticulum (ER) retrieval motif on the carboxyl terminus [1].
Analytical, diagnostic and therapeutic context of SURF4
- Immunofluorescence analysis of the three surf-4 myc chimeras yielded a cytoplasmic staining pattern [1].
References
- The surf-4 gene encodes a novel 30 kDa integral membrane protein. Reeves, J.E., Fried, M. Mol. Membr. Biol. (1995) [Pubmed]
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