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Gene Review

TULP3  -  tubby like protein 3

Homo sapiens

Synonyms: TUBL3, Tubby-like protein 3, Tubby-related protein 3
 
 
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High impact information on TULP3

  • Tub and the genes that encode three tubby-like proteins (TULP1- TULP3) form a novel, small gene family that plays an important role in maintenance and function of neuronal cells during development and post-differentiation [1].
  • We also report that TULP3 maps to human chromosome 12p13 [2].
  • TULP3 is detected at high levels in human RNA from testis, ovaries, thyroid, and spinal chord [2].
  • The murine homolog, Tulp3, maps to the telomere of mouse chromosome 6 [2].

References

  1. The tubby-like proteins, a family with roles in neuronal development and function. Ikeda, A., Nishina, P.M., Naggert, J.K. J. Cell. Sci. (2002) [Pubmed]
  2. Molecular characterization of a novel tubby gene family member, TULP3, in mouse and humans. Nishina, P.M., North, M.A., Ikeda, A., Yan, Y., Naggert, J.K. Genomics (1998) [Pubmed]
 
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