Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

UBE2L4 - ubiquitin-conjugating enzyme E2L 4

Homo sapiens

Ardley, H.C. et al., Ardley, H.C. et al.

Ardley, Moynihan, Markham, Robinson,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on UBE2L4

We have used the approach to isolate a fourth member of the UBE2L gene family, UBE2L4, and located it on chromosome 19q13.1-->q13 [1].
Rapid isolation of genomic clones for individual members of human multigene families: identification and localisation of UBE2L4, a novel member of a ubiquitin conjugating enzyme dispersed gene family [1].
Promoter characterisation of UBE2L1, UBE2L3 and UBE2L4 5'-upstream regions was performed to establish which are transcribed under normal physiological conditions and after heat shock [2].

Biological context of UBE2L4

These data strongly suggest that UBE2L1 and UBE2L4 are likely to encode pseudogenes [2].

Anatomical context of UBE2L4

No evidence for the presence of UBE2L1 or UBE2L4 transcripts was observed in human or murine tissues and cell lines [2].

References

Rapid isolation of genomic clones for individual members of human multigene families: identification and localisation of UBE2L4, a novel member of a ubiquitin conjugating enzyme dispersed gene family. Ardley, H.C., Moynihan, T.P., Thompson, J., Leek, J.P., Markham, A.F., Robinson, P.A. Cytogenet. Cell Genet. (1997) [Pubmed]
Promoter analysis of the human ubiquitin-conjugating enzyme gene family UBE2L1-4, including UBE2L3 which encodes UbcH7. Ardley, H.C., Moynihan, T.P., Markham, A.F., Robinson, P.A. Biochim. Biophys. Acta (2000) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg