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Gene Review:

Cmtm2a - CKLF-like MARVEL transmembrane domain...

Mus musculus

Synonyms: 1700001K04Rik, 1700041N15Rik, 1700063K20Rik, AI449770, ARR19, ...

Kersemans, V. et al., Li, T. et al.

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High impact information on Cmtm2a

For further study, we cloned the two mouse genes by EST assembly and RT-PCR methods and designated them as mouse Cklfsf2a and Cklfsf2b [1].
METHODS: Transport type characterisation in vitro in A549, A2058, C6, C32, Capan2, EF43fgf4, HT29 and R1M cells with [(123)I]-2-iodo-L: -phenylalanine was performed using the method described by Shotwell et al [2].

Analytical, diagnostic and therapeutic context of Cmtm2a

Molecular cloning and identification of mouse Cklfsf2a and Cklfsf2b, two homologues of human CKLFSF2 [1].
Subsequently, [(123)I]-2-iodo-L: -phenylalanine and [(123)I]-2-iodo-D: -phenylalanine tumour uptake and biodistribution were evaluated using dynamic planar imaging and/or dissection in A549, A2058, C6, C32, Capan2, EF43fgf4, HT29 and R1M inoculated athymic mice [2].

References

Molecular cloning and identification of mouse Cklfsf2a and Cklfsf2b, two homologues of human CKLFSF2. Li, T., Han, W., Yang, T., Ding, P., Rui, M., Liu, D., Wang, Y., Ma, D. Int. J. Biochem. Cell Biol. (2006) [Pubmed]
(123/125)I-labelled 2-iodo-L: -phenylalanine and 2-iodo-D: -phenylalanine: comparative uptake in various tumour types and biodistribution in mice. Kersemans, V., Cornelissen, B., Kersemans, K., Bauwens, M., Dierckx, R.A., De Spiegeleer, B., Mertens, J., Slegers, G. Eur. J. Nucl. Med. Mol. Imaging (2006) [Pubmed]

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