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Gene Review

Cabp4  -  calcium binding protein 4

Mus musculus

Synonyms: 2410038D05Rik, CaBP4, Calcium-binding protein 4
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High impact information on Cabp4

  • RESULTS: The thickness of the outer plexiform layer and the number of photoreceptor terminals in Cabp4(-/-)Gnat1(-/-) mice were reduced to levels similar to those of Cabp4(-/-) mice [1].
  • In this study, double CaBP4/rod alpha-transducin knockout (Cabp4(-/-)Gnat1(-/-)) mice lacking the rod-mediated component of electrophysiologic responses were generated and analyzed to investigate the role of CaBP4 in cones [1].
  • This and a previous study reveal that CaBP4 is critical for signal transmission from rods and cones to second-order neurons [1].


  1. A critical role of CaBP4 in the cone synapse. Maeda, T., Lem, J., Palczewski, K., Haeseleer, F. Invest. Ophthalmol. Vis. Sci. (2005) [Pubmed]
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