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Gene Review:

GRP-3 - glycine-rich protein 3

Arabidopsis thaliana

Synonyms: ARABIDOPSIS GLYCINE RICH PROTEIN 3, ATGRP-3, ATGRP3, GLYCINE-RICH PROTEIN 3, GRP3, ...

Park, A.R. et al., Yang, E.J. et al.

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High impact information on GRP-3

Moreover, exogenously added AtGRP-3 up-regulates the expression of Wak1, AtGRP-3, and PR-1 (for pathogenesis-related) in protoplasts [1].
Interaction of the Arabidopsis receptor protein kinase Wak1 with a glycine-rich protein, AtGRP-3 [1].
Further in vitro binding studies indicated that AtGRP-3 is the only isoform among the six tested AtGRPs that specifically interacts with Waks, and the cysteine-rich carboxyl terminus of AtGRP-3 is essential for its binding to Wak1 [1].
Oxygen-evolving enhancer protein 2 is phosphorylated by glycine-rich protein 3/wall-associated kinase 1 in Arabidopsis [2].

Associations of GRP-3 with chemical compounds

By the yeast two-hybrid screen, we found that a glycine-rich extracellular protein, AtGRP-3, binds to the extracellular domain of Wak1 [1].
Wak1 and AtGRP-3 are both induced by salicylic acid treatment [1].

Other interactions of GRP-3

Binding of AtGRP-3 to Wak1 is shown to be crucial for the integrity of the complex [1].

Analytical, diagnostic and therapeutic context of GRP-3

In this study, we sought to determine the downstream molecules of the AtGRP-3/WAK1 signaling pathway, by using two-dimensional gel electrophoresis combined with Edman sequencing and matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry (MALDI-TOF MS) [2].

References

Interaction of the Arabidopsis receptor protein kinase Wak1 with a glycine-rich protein, AtGRP-3. Park, A.R., Cho, S.K., Yun, U.J., Jin, M.Y., Lee, S.H., Sachetto-Martins, G., Park, O.K. J. Biol. Chem. (2001) [Pubmed]
Oxygen-evolving enhancer protein 2 is phosphorylated by glycine-rich protein 3/wall-associated kinase 1 in Arabidopsis. Yang, E.J., Oh, Y.A., Lee, E.S., Park, A.R., Cho, S.K., Yoo, Y.J., Park, O.K. Biochem. Biophys. Res. Commun. (2003) [Pubmed]

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