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Gene Review

CLPP  -  caseinolytic mitochondrial matrix...

Homo sapiens

Synonyms: ATP-dependent Clp protease proteolytic subunit, mitochondrial, DFNB81, Endopeptidase Clp, PRLTS3
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High impact information on CLPP

  • All patients underwent new CLPP measurement and a standard, complete urodynamic investigation, including filling cystometry with abdominal LPP and urethral pressure profile at rest [1].
  • Leak point pressure is determined by increasing abdominal pressure, which can be done with a Valsalva maneuver or coughing, that is Valsalva LPP and cough LPP (CLPP) [1].
  • At a minimum, measures of microbial biomass, respiration, and N mineralization and a community profiling method (e.g., DGGE, PLFA, or CLPP) should be included [2].
  • The major CLSP polyamine was spermidine while spermine exceeded the other two polyamines (putrescine and spermidine) in CLPP [3].

Associations of CLPP with chemical compounds

  • About 25% of the polyamines associated with CLSP and CLPP were covalently bound with the exception of CLSP putrescine where 62.1% was covalently bound [3].


  1. Evaluation of minimally invasive analysis system for cough leak point pressure measurement. Kocjancic, E., Tarrano, E., Panella, M., Crivellaro, S., Smith, J.J., Maso, G., Favro, M., Ceratti, G., Gontero, P., Frea, B. J. Urol. (2004) [Pubmed]
  2. The use of microorganisms in ecological soil classification and assessment concepts. Winding, A., Hund-Rinke, K., Rutgers, M. Ecotoxicol. Environ. Saf. (2005) [Pubmed]
  3. Polyamine metabolism in McCoy cells: II. Cellular origin of excreted polyamine conjugated proteins. Fan, M.Z., Chan, W.Y., Rennert, O.M. Physiological chemistry and physics and medical NMR. (1983) [Pubmed]
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