The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

HCF152  -  RNA binding protein HCF152

Arabidopsis thaliana

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on HCF152

  • In addition, we found that HCF152 is an RNA binding protein that binds certain areas of the petB transcript [1].
  • These data and additional experiments with the cytochrome b(6)f complex mutant hcf152, which is defective in 3' psbH processing, suggest that only those psbH-containing transcripts that are processed at their -45 5' ends can be translated [2].
  • To understand the molecular mechanism of how HCF152 modulates chloroplast gene expression, the molecular and biochemical properties should be revealed [3].
  • It was found that two HCF152 polypeptides bind to form a homodimer, and that this binding is impaired by a single amino acid substitute near the carboxyl terminus, replacing leucine with proline [3].

Other interactions of HCF152

  • Recombinant HCF152 bound with higher affinity RNA molecules, resembling the petB exon-intron junctions, as well as several other molecules [3].


  1. HCF152, an Arabidopsis RNA binding pentatricopeptide repeat protein involved in the processing of chloroplast psbB-psbT-psbH-petB-petD RNAs. Meierhoff, K., Felder, S., Nakamura, T., Bechtold, N., Schuster, G. Plant Cell (2003) [Pubmed]
  2. The nucleus-encoded HCF107 gene of Arabidopsis provides a link between intercistronic RNA processing and the accumulation of translation-competent psbH transcripts in chloroplasts. Felder, S., Meierhoff, K., Sane, A.P., Meurer, J., Driemel, C., Plücken, H., Klaff, P., Stein, B., Bechtold, N., Westhoff, P. Plant Cell (2001) [Pubmed]
  3. RNA-binding properties of HCF152, an Arabidopsis PPR protein involved in the processing of chloroplast RNA. Nakamura, T., Meierhoff, K., Westhoff, P., Schuster, G. Eur. J. Biochem. (2003) [Pubmed]
WikiGenes - Universities