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Gene Review:

petB - cytochrome b6

Arabidopsis thaliana

Jahns, P. et al., Meierhoff, K. et al., Baker, M.E. et al., Nakamura, T. et al.

Meierhoff, Felder, Nakamura, Bechtold, Schuster, Jahns, Graf, Munekage, Shikanai,

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Disease relevance of petB

In both mutants, reduced amounts of spliced petB RNAs (encoding the cytochrome b(6) subunit) were detected, thus explaining the observed protein deficiencies [1].

High impact information on petB

In addition, we found that HCF152 is an RNA binding protein that binds certain areas of the petB transcript [1].
Additionally, mutant hcf152-1 is affected in the accumulation of transcripts cleaved between the genes psbH and petB [1].
Single point mutation in the Rieske iron-sulfur subunit of cytochrome b6/f leads to an altered pH dependence of plastoquinol oxidation in Arabidopsis [2].
Spinach CSP41 is part of a protein complex that binds to the 3' untranslated region (UTR) of petD precursor-mRNA, a chloroplast gene encoding subunit IV of the cytochrome b6/f complex [3].

Biological context of petB

The pgr1 mutant of Arabidopsis thaliana carries a single point mutation (P194L) in the Rieske subunit of the cytochrome b6/f (cyt b6/f) complex and is characterised by a reduced electron transport activity at saturating light intensities in vivo [2].

Other interactions of petB

Recombinant HCF152 bound with higher affinity RNA molecules, resembling the petB exon-intron junctions, as well as several other molecules [4].

References

HCF152, an Arabidopsis RNA binding pentatricopeptide repeat protein involved in the processing of chloroplast psbB-psbT-psbH-petB-petD RNAs. Meierhoff, K., Felder, S., Nakamura, T., Bechtold, N., Schuster, G. Plant Cell (2003) [Pubmed]
Single point mutation in the Rieske iron-sulfur subunit of cytochrome b6/f leads to an altered pH dependence of plastoquinol oxidation in Arabidopsis. Jahns, P., Graf, M., Munekage, Y., Shikanai, T. FEBS Lett. (2002) [Pubmed]
Spinach CSP41, an mRNA-binding protein and ribonuclease, is homologous to nucleotide-sugar epimerases and hydroxysteroid dehydrogenases. Baker, M.E., Grundy, W.N., Elkan, C.P. Biochem. Biophys. Res. Commun. (1998) [Pubmed]
RNA-binding properties of HCF152, an Arabidopsis PPR protein involved in the processing of chloroplast RNA. Nakamura, T., Meierhoff, K., Westhoff, P., Schuster, G. Eur. J. Biochem. (2003) [Pubmed]

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petB	Oryza sativa Japonica Group
BI4	Saccharomyces cerevisiae S288c

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