Gene Review:
GPK1 - glyoxysomal protein kinase 1
Arabidopsis thaliana
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High impact information on GPK1
- Immuno-inhibition of phosphorylation in glyoxysomes suggested that GPK1 phosphorylates a 40-kDa protein [1].
- The amino acid sequence deduced from GPK1 cDNA has a hydrophobic region, a putative protein kinase domain, and a possible PTS1 motif [1].
- Analysis of suborganellar localization and protease sensitivity showed that GPK1 is localized on glyoxysomal membranes as a peripheral membrane protein and that the putative kinase domain is located inside the glyoxysomes [1].
Anatomical context of GPK1
- Immunoblot analysis using fractions collected on a Percoll density gradient confirmed that GPK1 is localized in glyoxysomes [1].
Analytical, diagnostic and therapeutic context of GPK1
References
- Novel glyoxysomal protein kinase, GPK1, identified by proteomic analysis of glyoxysomes in etiolated cotyledons of Arabidopsis thaliana. Fukao, Y., Hayashi, M., Hara-Nishimura, I., Nishimura, M. Plant Cell Physiol. (2003) [Pubmed]
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