Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

KLRC4 - killer cell lectin-like receptor subfamily...

Homo sapiens

Synonyms: NK cell receptor F, NKG2-F, NKG2-F type II integral membrane protein, NKG2-F-activating NK receptor, NKG2F

Glienke, J. et al., Plougastel, B. et al., Kim, D.K. et al.

Plougastel, Trowsdale,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on KLRC4

Despite the similarities with the other NKG2 genes, NKG2-F encodes a putative protein which does not contain any lectin domain [1].
NKG2F consists of only four exons and part of exon IV is in some cases spliced to the 5' end of the NKG2D transcript [2].
Human NKG2F is expressed and can associate with DAP12 [3].
We show that NKG2F is expressed as a protein in NK cells [3].

Anatomical context of KLRC4

Cloning of NKG2-F, a new member of the NKG2 family of human natural killer cell receptor genes [1].

References

Cloning of NKG2-F, a new member of the NKG2 family of human natural killer cell receptor genes. Plougastel, B., Trowsdale, J. Eur. J. Immunol. (1997) [Pubmed]
The genomic organization of NKG2C, E, F, and D receptor genes in the human natural killer gene complex. Glienke, J., Sobanov, Y., Brostjan, C., Steffens, C., Nguyen, C., Lehrach, H., Hofer, E., Francis, F. Immunogenetics (1998) [Pubmed]
Human NKG2F is expressed and can associate with DAP12. Kim, D.K., Kabat, J., Borrego, F., Sanni, T.B., You, C.H., Coligan, J.E. Mol. Immunol. (2004) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.