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Gene Review:

Mkln1 - muskelin 1, intracellular mediator...

Rattus norvegicus

Synonyms: Msk, Muskelin

Ledee, D.R. et al., Hasegawa, H. et al.

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High impact information on Mkln1

A specific interaction between muskelin and the cyclin-dependent kinase 5 activator p39 promotes peripheral localization of muskelin [1].
Co-expression of p39 and muskelin in COS1 cells or lens epithelial cells altered the intracellular localization of muskelin, recruiting it to the cell periphery [1].
Receptor isoform-specific interaction of prostaglandin EP3 receptor with muskelin [2].
Analysis by confocal microscopy indicated that the isoform and muskelin were distributed at the plasma membrane in transfected cells [2].

Analytical, diagnostic and therapeutic context of Mkln1

Immunohistochemistry detected muskelin in the developing lens and in other tissues, including brain and muscle [1].

References

A specific interaction between muskelin and the cyclin-dependent kinase 5 activator p39 promotes peripheral localization of muskelin. Ledee, D.R., Gao, C.Y., Seth, R., Fariss, R.N., Tripathi, B.K., Zelenka, P.S. J. Biol. Chem. (2005) [Pubmed]
Receptor isoform-specific interaction of prostaglandin EP3 receptor with muskelin. Hasegawa, H., Katoh, H., Fujita, H., Mori, K., Negishi, M. Biochem. Biophys. Res. Commun. (2000) [Pubmed]

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mkln1	Danio rerio
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