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Gene Review

Apba2  -  amyloid beta (A4) precursor protein...

Rattus norvegicus

Synonyms: Adapter protein X11beta, Amyloid beta A4 precursor protein-binding family A member 2, Mint-2, Mint2, Neuron-specific X11L protein, ...
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High impact information on Apba2

  • In addition, tamalin forms a complex with PSD-95 and Mint2/X11beta/X11L by mechanisms different from the PDZ-mediated interaction [1].
  • RT-PCR analysis revealed that apart from Mint1, RINm5F cells and rat islets also transcribed the mRNAs for Mint2 and Mint3 [2].


  1. Tamalin is a scaffold protein that interacts with multiple neuronal proteins in distinct modes of protein-protein association. Kitano, J., Yamazaki, Y., Kimura, K., Masukado, T., Nakajima, Y., Nakanishi, S. J. Biol. Chem. (2003) [Pubmed]
  2. Mint1, a Munc-18-interacting protein, is expressed in insulin-secreting beta-cells. Zhang, W., Lilja, L., Bark, C., Berggren, P.O., Meister, B. Biochem. Biophys. Res. Commun. (2004) [Pubmed]
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