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Gene Review:

MBD7 - methyl-CpG-binding domain-containing...

Arabidopsis thaliana

Synonyms: ARABIDOPSIS THALIANA METHYL-CPG-BINDING DOMAIN 7, ATMBD7, MMN10.2, MMN10_2, methyl-CPG-binding domain 7

Zemach, A. et al., Zemach, A. et al.

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High impact information on MBD7

By expressing in wild-type cells AtMBDs fused to green fluorescent protein (GFP), we showed that AtMBD7 was evenly distributed at all chromocenters, whereas AtMBD5 and 6 showed preference for two perinucleolar chromocenters adjacent to nucleolar organizing regions [1].
Our results suggest that AtMBD5, AtMBD6, and AtMBD7 are likely to function in Arabidopsis plants as mediators of the CpG methylation, linking DNA methylation-induced gene silencing with histone deacetylation [2].

References

DDM1 binds Arabidopsis methyl-CpG binding domain proteins and affects their subnuclear localization. Zemach, A., Li, Y., Wayburn, B., Ben-Meir, H., Kiss, V., Avivi, Y., Kalchenko, V., Jacobsen, S.E., Grafi, G. Plant Cell (2005) [Pubmed]
Characterization of Arabidopsis thaliana methyl-CpG-binding domain (MBD) proteins. Zemach, A., Grafi, G. Plant J. (2003) [Pubmed]

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