Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

IAA12 - indole-3-acetic acid inducible 12

Arabidopsis thaliana

Synonyms: BDL, BODENLOS, T1G11.20, T1G11_20

Hamann, T. et al., Weijers, D. et al., Dharmasiri, N. et al.

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High impact information on IAA12

The Arabidopsis BODENLOS gene encodes an auxin response protein inhibiting MONOPTEROS-mediated embryo patterning [1].
Here we show that the bodenlos phenotype results from an amino-acid exchange in the conserved degradation domain of IAA12 [1].
Correspondingly, all TIR1/AFB proteins interact with BDL, and BDL is stabilized in triple mutant plants [2].

Biological context of IAA12

Although both bdl and shy2-2 proteins inhibited MP/ARF5-dependent reporter gene activation, shy2-2 was much less efficient than bdl to interfere with embryonic root initiation when expressed from the BDL promoter [3].

References

The Arabidopsis BODENLOS gene encodes an auxin response protein inhibiting MONOPTEROS-mediated embryo patterning. Hamann, T., Benkova, E., Bäurle, I., Kientz, M., Jürgens, G. Genes Dev. (2002) [Pubmed]
Plant development is regulated by a family of auxin receptor F box proteins. Dharmasiri, N., Dharmasiri, S., Weijers, D., Lechner, E., Yamada, M., Hobbie, L., Ehrismann, J.S., Jürgens, G., Estelle, M. Dev. Cell (2005) [Pubmed]
Developmental specificity of auxin response by pairs of ARF and Aux/IAA transcriptional regulators. Weijers, D., Benkova, E., Jäger, K.E., Schlereth, A., Hamann, T., Kientz, M., Wilmoth, J.C., Reed, J.W., Jürgens, G. EMBO J. (2005) [Pubmed]

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