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Gene Review

PCGF6  -  polycomb group ring finger 6

Homo sapiens

Synonyms: MBLR, Mel18 and Bmi1-like RING finger, Polycomb group RING finger protein 6, RING finger protein 134, RNF134
 
 
 
 
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High impact information on PCGF6

  • In addition, we find that serine 32 of MBLR is specifically phosphorylated during mitosis, most likely by CDK7, a component of the basal transcriptional machinery [1].
  • Immunocytochemical analysis reveals that MBLR protein is localized in a fine-grained distribution throughout the nucleoplasm in interphase cultured cells and in a fainter diffuse cytoplasmic distribution in mitotic cells [1].

References

  1. MBLR, a new RING finger protein resembling mammalian Polycomb gene products, is regulated by cell cycle-dependent phosphorylation. Akasaka, T., Takahashi, N., Suzuki, M., Koseki, H., Bodmer, R., Koga, H. Genes Cells (2002) [Pubmed]
 
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