Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

ZNF282 - zinc finger protein 282

Homo sapiens

Synonyms: HTLV-I U5RE-binding protein 1, HUB-1, HUB1, Zinc finger protein 282

Itoh, M. et al., Okumura, K. et al.

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Disease relevance of ZNF282

Thus, we propose that HUB1 is a new type repressor and plays an important role in the HTLV-I U5-mediated repression [1].
HUB1 is an autoantigen frequently eliciting humoral immune response in patients with adult T cell leukemia [2].

High impact information on ZNF282

HUB1, a novel Krüppel type zinc finger protein, represses the human T cell leukemia virus type I long terminal repeat-mediated expression [1].
One of the identified cDNAs was homologous to the recently reported gene, HTLV-I U5RE binding protein 1 (HUB1) encoding a protein binding to a possible repressor element of the long terminal repeat of the human T lymphotropic virus type I (HTLV-I) [2].

References

HUB1, a novel Krüppel type zinc finger protein, represses the human T cell leukemia virus type I long terminal repeat-mediated expression. Okumura, K., Sakaguchi, G., Naito, K., Tamura, T., Igarashi, H. Nucleic Acids Res. (1997) [Pubmed]
HUB1 is an autoantigen frequently eliciting humoral immune response in patients with adult T cell leukemia. Itoh, M., Watanabe, M., Yamada, Y., Furukawa, K., Taniguchi, M., Hata, T., Schmitt, M., Ikeda, H., Yamaguchi, M., Ohno, T., Nakashima, K., Shiku, H. Int. J. Oncol. (1999) [Pubmed]

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