Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

CDKB2;1 - cyclin-dependent kinase B2-1

Arabidopsis thaliana

Synonyms: CYCLIN-DEPENDENT KINASE B2;1, F14G6.14, F14G6_14, cyclin-dependent kinase B2;1

Kono, A. et al.

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High impact information on CDKB2;1

Promoter analysis using the luciferase reporter gene showed that CDKB2;1 was expressed from early G2 to M phase, whereas CYCD4;1 was expressed throughout the cell cycle [1].
Our results suggest that CDKB2;1 and CYCD4;1 may form an active kinase complex during G2/M phase and control the development of particular tissues [1].
In Arabidopsis, we isolated cDNA encoding the D-type cyclin CYCD4;1 by a yeast (Saccharomyces cerevisiae) two-hybrid screening using CDKB2;1 as bait [1].

Analytical, diagnostic and therapeutic context of CDKB2;1

In situ hybridization of plant tissues revealed that both CDKB2;1 and CYCD4;1 transcripts accumulated in the shoot apical meristem, leaf primordia, vasculature of leaves, and tapetal cells in anthers [1].

References

Arabidopsis D-type cyclin CYCD4;1 is a novel cyclin partner of B2-type cyclin-dependent kinase. Kono, A., Umeda-Hara, C., Lee, J., Ito, M., Uchimiya, H., Umeda, M. Plant Physiol. (2003) [Pubmed]

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