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Gene Review

MAK31  -  Mak31p

Saccharomyces cerevisiae S288c

Synonyms: L-A virus GAG protein N-acetyltransferase subunit MAK31, LSM9, Maintenance of killer protein 31, N-alpha-acetyltransferase 38, NatC auxiliary subunit, N-terminal acetyltransferase C complex subunit MAK31, ...
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High impact information on MAK31

  • A screen for multicopy suppressors yielded plasmids carrying the RSC6 and MAK31 loci [1].
  • We show herein EGAP is the mammalian/zebrafish homologue of yeast Mak10p, one subunit of the yeast NatC complex, and describe the cloning of its binding partners Mak3 and Mak31 [2].
  • Disruption of YCR020c-a/MAK31 brought about a loss of dsRNA without affecting the temperature sensitive phenotype [3].


  1. Direct interaction between Rsc6 and Rsc8/Swh3,two proteins that are conserved in SWI/SNF-related complexes. Treich, I., Ho, L., Carlson, M. Nucleic Acids Res. (1998) [Pubmed]
  2. Embryonic growth-associated protein is one subunit of a novel N-terminal acetyltransferase complex essential for embryonic vascular development. Wenzlau, J.M., Garl, P.J., Simpson, P., Stenmark, K.R., West, J., Artinger, K.B., Nemenoff, R.A., Weiser-Evans, M.C. Circ. Res. (2006) [Pubmed]
  3. Dissecting the pet18 mutation in Saccharomyces cerevisiae: HTL1 encodes a 7-kDa polypeptide that interacts with components of the RSC complex. Lu, Y.M., Lin, Y.R., Tsai, A., Hsao, Y.S., Li, C.C., Cheng, M.Y. Mol. Genet. Genomics (2003) [Pubmed]
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