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Gene Review

ATO3  -  putative ammonium permease ATO3

Saccharomyces cerevisiae S288c

Synonyms: Ammonia transport outward protein 3, D9481.20, D9509.4, YDR384C
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High impact information on ATO3

  • ATO3 encoding a putative outward ammonium transporter is an RTG-independent retrograde responsive gene regulated by GCN4 and the Ssy1-Ptr3-Ssy5 amino acid sensor system [1].
  • We show that Ato3p-green fluorescent protein is preferentially localized to the plasma membrane of mother cells. rhoo petites express more Ato3p-green fluorescent protein in their plasma membrane than do rho+ cells, consistent with the elevated level of ATO3 transcripts in rhoo cells [1].
  • We present evidence that the three membrane proteins Ato1p, Ato2p, and Ato3p, members of the YaaH family, are involved in ammonia production in Saccharomyces cerevisiae colonies [2].

Other interactions of ATO3

  • The first involves GCN4, which is required for the bulk of ATO3 expression [1].


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