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Gene Review

RPL19A  -  ribosomal 60S subunit protein L19A

Saccharomyces cerevisiae S288c

Synonyms: 60S ribosomal protein L19-A, L23, RP15L, RP33, RPL23A, ...
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High impact information on RPL19A

  • RPL19A was also found to be adjacent to the chromosome II AAC3 gene, encoding the mitochondrial ADP/ATP carrier protein [1].
  • A gene designated RPL19A has been identified in the region downstream from the 3'-end of the Saccharomyces cerevisiae MIS1 gene encoding the mitochondrial C1-tetrahydrofolate synthase [1].
  • RPL19A is one of two functional copies of the YL19 gene located on chromosome II [1].
  • Nucleotide sequence and characterization of the Saccharomyces cerevisiae RPL19A gene encoding a homolog of the mammalian ribosomal protein L19 [1].
  • Yeast cells containing disruption of either RPL19A or RPL19B formed smaller colonies than wild-type strains; however, simultaneous deletion of both genes is lethal [2].

Biological context of RPL19A

  • The coding regions of the two yeast genes, RPL19A and RPL19B, differ in only 34 nucleotides, none of which lead to changes in the amino-acid sequences of the predicted protein of 189 amino acids [2].


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