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Gene Review

VAS1  -  valine--tRNA ligase

Saccharomyces cerevisiae S288c

Synonyms: ValRS, Valine--tRNA ligase, mitochondrial, Valyl-tRNA synthetase, YGR094W
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Disease relevance of VAS1


High impact information on VAS1

  • The longer class of VAS1 transcripts initiates upstream of both ATG codons located 138 base pairs away and the shorter class downstream of the first ATG [2].


  1. Selection of viral RNA-derived tRNA-like structures with improved valylation activities. Wientges, J., Pütz, J., Giegé, R., Florentz, C., Schwienhorst, A. Biochemistry (2000) [Pubmed]
  2. The yeast VAS1 gene encodes both mitochondrial and cytoplasmic valyl-tRNA synthetases. Chatton, B., Walter, P., Ebel, J.P., Lacroute, F., Fasiolo, F. J. Biol. Chem. (1988) [Pubmed]
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