Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

NOP8 - Nop8p

Saccharomyces cerevisiae S288c

Synonyms: 60S ribosome subunit biogenesis protein NOP8, Nucleolar protein 8, YOL144W

Zanchin, N.I. et al., Rosado, I.V. et al.

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High impact information on NOP8

Furthermore, coimmunoprecipitation and gel filtration analyses demonstrated that at least Npa2p, Dbp6p, Npa1p, Nop8p, and Rsa3p are present together in a subcomplex of low molecular mass whose integrity is independent of RNA [1].
Nip7p interacts with Nop8p, an essential nucleolar protein required for 60S ribosome biogenesis, and the exosome subunit Rrp43p [2].
Cells depleted of Nop8p contained reduced levels of free 60S ribosomes and polysomes and accumulated half-mer polysomes [2].

References

Characterization of Saccharomyces cerevisiae Npa2p (Urb2p) Reveals a Low-Molecular-Mass Complex Containing Dbp6p, Npa1p (Urb1p), Nop8p, and Rsa3p Involved in Early Steps of 60S Ribosomal Subunit Biogenesis. Rosado, I.V., Dez, C., Lebaron, S., Caizergues-Ferrer, M., Henry, Y., de la Cruz, J. Mol. Cell. Biol. (2007) [Pubmed]
Nip7p interacts with Nop8p, an essential nucleolar protein required for 60S ribosome biogenesis, and the exosome subunit Rrp43p. Zanchin, N.I., Goldfarb, D.S. Mol. Cell. Biol. (1999) [Pubmed]

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AGOS_AGR397C	Ashbya gossypii ATCC 10895
KLLA0E01937g	Kluyveromyces lactis NRRL Y-1140

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