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PDR10  -  ATP-binding cassette multidrug transporter...

Saccharomyces cerevisiae S288c

Synonyms: ATP-dependent permease PDR10, YOR328W
 
 
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High impact information on PDR10

  • We have identified two new ABC transporter-encoding genes, PDR10 and PDR15, which were up-regulated by the PDR1-3 mutation [1].
  • Although noncoding and coding sequences show substantial variability in ratios of polymorphism to divergence, two of the loci, MLS1 and PDR10, show a higher rate of polymorphism at noncoding compared to synonymous sites [2].
  • In addition, in vitro band shift assays demonstrate that a GST-Pdr1 fusion protein can bind to the PDREs of PDR10 and PDR15 [3].
  • Sequence of 29 kb around the PDR10 locus on the right arm of Saccharomyces cerevisiae chromosome XV: similarity to part of chromosome I [4].
 

Other interactions of PDR10

References

  1. ATPase and multidrug transport activities of the overexpressed yeast ABC protein Yor1p. Decottignies, A., Grant, A.M., Nichols, J.W., de Wet, H., McIntosh, D.B., Goffeau, A. J. Biol. Chem. (1998) [Pubmed]
  2. Hypervariable noncoding sequences in Saccharomyces cerevisiae. Fay, J.C., Benavides, J.A. Genetics (2005) [Pubmed]
  3. The yeast ATP binding cassette (ABC) protein genes PDR10 and PDR15 are novel targets for the Pdr1 and Pdr3 transcriptional regulators. Wolfger, H., Mahé, Y., Parle-McDermott, A., Delahodde, A., Kuchler, K. FEBS Lett. (1997) [Pubmed]
  4. Sequence of 29 kb around the PDR10 locus on the right arm of Saccharomyces cerevisiae chromosome XV: similarity to part of chromosome I. Parle-McDermott, A.G., Hand, N.J., Goulding, S.E., Wolfe, K.H. Yeast (1996) [Pubmed]
 
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