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Gene Review

SER33  -  phosphoglycerate dehydrogenase SER33

Saccharomyces cerevisiae S288c

Synonyms: 3-PGDH 2, D-3-phosphoglycerate dehydrogenase 2, YIL074C
 
 
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High impact information on SER33

  • Moreover, since phosphoglycerate dehydrogenase activity requires NAD(+) as cofactor, deletion of SER3 and SER33 markedly affected redox metabolism as shown by substrate and product analysis [1].
  • Based on these mRNA data together with data on enzyme activities, Ser33p is likely to be the main isoenzyme of the phosphoglycerate pathway during growth on glucose [1].

References

  1. Ser3p (Yer081wp) and Ser33p (Yil074cp) are phosphoglycerate dehydrogenases in Saccharomyces cerevisiae. Albers, E., Laizé, V., Blomberg, A., Hohmann, S., Gustafsson, L. J. Biol. Chem. (2003) [Pubmed]
 
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