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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

RIM9  -  Rim9p

Saccharomyces cerevisiae S288c

Synonyms: Regulator of IME2 protein 9, YM9916.02, YMR063W, pH-response regulator protein palI/RIM9
 
 
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High impact information on RIM9

  • We now show that the Aspergillus PalI pH signal transduction component is homologous to the Saccharomyces Rim9p meiotic signal transduction component throughout a region containing four hydrophobic, putative membrane-spanning segments [1].
  • We have also analyzed production of beta-galactosidase in strains that express a RIM1-lacZ fusion gene. beta-galactosidase exists primarily as a approximately 130 kD form in wild-type cells and as a approximately 190 kD form in rim9 mutants [2].
  • PAL2 encodes a putative 632-residue protein with six possible transmembrane segments, which differs from the transmembrane proteins Rim9p of S. cerevisiae and Pall of A. nidulans, but is homologous to A. nidulans Pa1H and to the product of the ORF YNL294c, a predicted polypeptide of unknown function in S. cerevisiae [3].

References

  1. Putative membrane components of signal transduction pathways for ambient pH regulation in Aspergillus and meiosis in saccharomyces are homologous. Denison, S.H., Negrete-Urtasun, S., Mingot, J.M., Tilburn, J., Mayer, W.A., Goel, A., Espeso, E.A., Peñalva, M.A., Arst, H.N. Mol. Microbiol. (1998) [Pubmed]
  2. Proteolytic activation of Rim1p, a positive regulator of yeast sporulation and invasive growth. Li, W., Mitchell, A.P. Genetics (1997) [Pubmed]
  3. Ambient pH signalling in ascomycetous yeasts involves homologues of the Aspergillus nidulans genes palF and paIH. Tréton, B., Blanchin-Roland, S., Lambert, M., Lépingle, A., Gaillardin, C. Mol. Gen. Genet. (2000) [Pubmed]
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