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Gene Review

TAF7  -  Taf7p

Saccharomyces cerevisiae S288c

Synonyms: TAF67, TAFII-67, TBP-associated factor 67 kDa, TBP-associated factor 7, Transcription initiation factor TFIID subunit 7, ...
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High impact information on TAF7

  • Deletion of Bdf1 or the Taf67 Bdf-interacting domain leads to defects in gene expression [1].
  • Using a yeast two-hybrid screen to identify proteins that interact with Taf67, we isolated Bromodomain factor 1 (Bdf1) and its homolog (Bdf2) [1].
  • Moreover, the N-terminal domain of TAF1 was mapped in lobe C, whereas the histone acetyltransferase domain resides in lobe A along with TAF7 [2].
  • Based on their predicted molecular weights, these genes have been designated TAF67, TAF61(68), TAF40, TAF23(25), TAF19(FUN81), and TAF17 [3].


  1. Bromodomain factor 1 corresponds to a missing piece of yeast TFIID. Matangkasombut, O., Buratowski, R.M., Swilling, N.W., Buratowski, S. Genes Dev. (2000) [Pubmed]
  2. Mapping key functional sites within yeast TFIID. Leurent, C., Sanders, S.L., Demény, M.A., Garbett, K.A., Ruhlmann, C., Weil, P.A., Tora, L., Schultz, P. EMBO J. (2004) [Pubmed]
  3. Yeast homologues of higher eukaryotic TFIID subunits. Moqtaderi, Z., Yale, J.D., Struhl, K., Buratowski, S. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
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