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Gene Review

ACA1  -  Aca1p

Saccharomyces cerevisiae S288c

Synonyms: ATF/CREB activator 1, YER045C
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High impact information on ACA1

  • Aca1 and Aca2, ATF/CREB activators in Saccharomyces cerevisiae, are important for carbon source utilization but not the response to stress [1].
  • Genetic epistasis studies support models in which Aca1 and Gpa1 are necessary and sufficient components that cooperate to activate adenylyl cyclase [2].
  • By molecular and genetic approaches, Aca1 was shown to play a critical role in mating by regulating cell fusion and filamentous growth in a cAMP-dependent manner [2].


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