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Gene Review:

rhaB - rhamnulokinase

Escherichia coli O157:H7 str. Sakai

Badia, J. et al., Badía, J. et al.

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Disease relevance of ECs4831

However, rhamnulose kinase did not phosphorylate L-xylulose sufficiently to support the growth of wild-type E. coli on L-lyxose [1].

High impact information on ECs4831

Mutants able to grow on L-lyxose were analyzed and found to have a mutated rhamnulose kinase which phosphorylated L-xylulose as efficiently as the wild-type enzyme phosphorylated L-rhamnulose [1].
L-Rhamnose is metabolized in E. coli by a system that consists of a rhamnose permease, rhamnose isomerase, rhamnulose kinase, and rhamnulose-1-phosphate aldolase, which yields the degradation products dihydroxyacetone phosphate and L-lactaldehyde [1].
Protein products of 47 kDa, 52-54 kDa and 32 kDa have been assigned to rhamnose isomerase, rhamnulose kinase and rhamnulose 1-phosphate aldolase respectively [2].

References

L-lyxose metabolism employs the L-rhamnose pathway in mutant cells of Escherichia coli adapted to grow on L-lyxose. Badia, J., Gimenez, R., Baldomá, L., Barnes, E., Fessner, W.D., Aguilar, J. J. Bacteriol. (1991) [Pubmed]
Identification of the rhaA, rhaB and rhaD gene products from Escherichia coli K-12. Badía, J., Baldomà, L., Aguilar, J., Boronat, A. FEMS Microbiol. Lett. (1989) [Pubmed]

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