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Gene Review:

GPR55 - G protein-coupled receptor 55

Homo sapiens

Synonyms: G-protein coupled receptor 55

Sawzdargo, M. et al., Baker, D. et al.

Baker, Pryce, Davies, Hiley,

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High impact information on GPR55

Thus, GPR55 might represent a new cannabinoid receptor [1].
GPR55 and GPR52 encode receptors of 319 and 361 amino acids, respectively [2].
GPR55 gene was mapped to chromosome 2q37, using fluorescence in situ hybridization (FISH), and its mRNA transcripts have been detected in the caudate nucleus and putamen, but not in five other brain regions [2].
A partial cDNA clone obtained from the IMAGE Consortium of GPR55 was used to screen a human genomic library to acquire the full length gene [2].

References

In silico patent searching reveals a new cannabinoid receptor. Baker, D., Pryce, G., Davies, W.L., Hiley, C.R. Trends Pharmacol. Sci. (2006) [Pubmed]
Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain. Sawzdargo, M., Nguyen, T., Lee, D.K., Lynch, K.R., Cheng, R., Heng, H.H., George, S.R., O'Dowd, B.F. Brain Res. Mol. Brain Res. (1999) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

GPR55	Bos taurus
GPR55	Canis lupus familiaris
LOC793909	Danio rerio
GPR55	Gallus gallus
LOC711323	Macaca mulatta
Gpr55	Mus musculus
GPR55	Pan troglodytes
Gpr55	Rattus norvegicus
LOC100490418	Xenopus (Silurana) tropicalis

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