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Gene Review

sulD  -  bifunctional folate synthesis protein

Streptococcus pneumoniae R6

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Disease relevance of sulD

  • DNA sequence of folate biosynthesis gene sulD, encoding hydroxymethyldihydropterin pyrophosphokinase in Streptococcus pneumoniae, and characterization of the enzyme [1].
  • Subcloning of the sulD gene in an Escherichia coli expression vector increased expression of the pyrophosphokinase 1,000-fold over the level produced by a single copy of the chromosomal gene [1].

High impact information on sulD


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