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Chemical Compound Review

SureCN230712     2-amino-6-(hydroxymethyl)- 7,8-dihydro-1H...

Synonyms: SureCN849650, SureCN851106, AG-K-81155, CHEBI:17083, CHEBI:44841, ...
 
 
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Disease relevance of C01300

 

High impact information on C01300

 

Biological context of C01300

 

Associations of C01300 with other chemical compounds

 

Gene context of C01300

 

Analytical, diagnostic and therapeutic context of C01300

References

  1. Equilibrium and kinetic studies of substrate binding to 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Escherichia coli. Bermingham, A., Bottomley, J.R., Primrose, W.U., Derrick, J.P. J. Biol. Chem. (2000) [Pubmed]
  2. The structure and function of the 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Haemophilus influenzae. Hennig, M., Dale, G.E., D'arcy, A., Danel, F., Fischer, S., Gray, C.P., Jolidon, S., Müller, F., Page, M.G., Pattison, P., Oefner, C. J. Mol. Biol. (1999) [Pubmed]
  3. Crystal structure of the bifunctional dihydroneopterin aldolase/6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Streptococcus pneumoniae. Garçon, A., Levy, C., Derrick, J.P. J. Mol. Biol. (2006) [Pubmed]
  4. Crystal structure and reaction mechanism of 7,8-dihydroneopterin aldolase from Staphylococcus aureus. Hennig, M., D'Arcy, A., Hampele, I.C., Page, M.G., Oefner, C., Dale, G.E. Nat. Struct. Biol. (1998) [Pubmed]
  5. The three-dimensional structure of the bifunctional 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase/dihydropteroate synthase of Saccharomyces cerevisiae. Lawrence, M.C., Iliades, P., Fernley, R.T., Berglez, J., Pilling, P.A., Macreadie, I.G. J. Mol. Biol. (2005) [Pubmed]
  6. Biosynthesis of tetrahydrofolate in plants: crystal structure of 7,8-dihydroneopterin aldolase from Arabidopsis thaliana reveals a novel adolase class. Bauer, S., Schott, A.K., Illarionova, V., Bacher, A., Huber, R., Fischer, M. J. Mol. Biol. (2004) [Pubmed]
  7. Folate synthesis in higher-plant mitochondria: coupling between the dihydropterin pyrophosphokinase and the dihydropteroate synthase activities. Mouillon, J.M., Ravanel, S., Douce, R., Rébeillé, F. Biochem. J. (2002) [Pubmed]
  8. A bifunctional protein in the folate biosynthetic pathway of Streptococcus pneumoniae with dihydroneopterin aldolase and hydroxymethyldihydropterin pyrophosphokinase activities. Lopez, P., Lacks, S.A. J. Bacteriol. (1993) [Pubmed]
  9. Sequence variation of the hydroxymethyldihydropterin pyrophosphokinase: dihydropteroate synthase gene in lines of the human malaria parasite, Plasmodium falciparum, with differing resistance to sulfadoxine. Brooks, D.R., Wang, P., Read, M., Watkins, W.M., Sims, P.F., Hyde, J.E. Eur. J. Biochem. (1994) [Pubmed]
  10. Folate biosynthesis pseudogenes, PsifolP and PsifolK, and an O-sialoglycoprotein endopeptidase gene homolog in the phytoplasma genome. Davis, R.E., Jomantiene, R., Zhao, Y., Dally, E.L. DNA Cell Biol. (2003) [Pubmed]
  11. The hydroxymethyldihydropterin pyrophosphokinase domain of the multifunctional folic acid synthesis Fas protein of Pneumocystis carinii expressed as an independent enzyme in Escherichia coli: refolding and characterization of the recombinant enzyme. Ballantine, S.P., Volpe, F., Delves, C.J. Protein Expr. Purif. (1994) [Pubmed]
  12. DNA sequence of folate biosynthesis gene sulD, encoding hydroxymethyldihydropterin pyrophosphokinase in Streptococcus pneumoniae, and characterization of the enzyme. Lopez, P., Greenberg, B., Lacks, S.A. J. Bacteriol. (1990) [Pubmed]
  13. Unusual conformational changes in 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as revealed by X-ray crystallography and NMR. Xiao, B., Shi, G., Gao, J., Blaszczyk, J., Liu, Q., Ji, X., Yan, H. J. Biol. Chem. (2001) [Pubmed]
  14. Catalytic roles of arginine residues 82 and 92 of Escherichia coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: site-directed mutagenesis and biochemical studies. Li, Y., Wu, Y., Blaszczyk, J., Ji, X., Yan, H. Biochemistry (2003) [Pubmed]
 
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