Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

pdxK - pyridoxal-pyridoxamine...

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK2413, JW2411, pdxL, thiJ, yfeI

Safo, M.K. et al., Yang, Y. et al.

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Disease relevance of pdxK

Identification of the pdxK gene that encodes pyridoxine (vitamin B6) kinase in Escherichia coli K-12 [1].

High impact information on pdxK

The pdxK and pdxY genes have been found to code for pyridoxal kinases, enzymes involved in the pyridoxal phosphate salvage pathway [2].
Crystal structure of pyridoxal kinase from the Escherichia coli pdxK gene: implications for the classification of pyridoxal kinases [2].
P1 transduction and PCR mapping and DNA sequence analysis showed that pdxK was adjacent to the crr sugar transport gene (53.95 min) [1].

Associations of pdxK with chemical compounds

We isolated a miniTn10(Cmr) insertion mutant lacking pyridoxine (PN) kinase and cloned the structural gene, designated pdxK, by complementation [1].

References

Identification of the pdxK gene that encodes pyridoxine (vitamin B6) kinase in Escherichia coli K-12. Yang, Y., Zhao, G., Winkler, M.E. FEMS Microbiol. Lett. (1996) [Pubmed]
Crystal structure of pyridoxal kinase from the Escherichia coli pdxK gene: implications for the classification of pyridoxal kinases. Safo, M.K., Musayev, F.N., di Salvo, M.L., Hunt, S., Claude, J.B., Schirch, V. J. Bacteriol. (2006) [Pubmed]

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