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Gene Review:

gcvP - glycine decarboxylase, PLP-dependent,...

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK2898, JW2871

Turner, S.J. et al., Okamura-Ikeda, K. et al., Stauffer, L.T. et al.

Turner, Lewis, Bellamy,

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Disease relevance of gcvP

The nucleotide (nt) sequence of the Escherichia coli gcvP gene was determined [1].

High impact information on gcvP

The marker maps to a region of the chromosome located immediately downstream from the gene encoding the glycine decarboxylase P-protein (gcvP) [2].
DNA sequences from marker-positive and marker-negative isolates exhibit an abrupt loss of homology immediately downstream from the transcription termination point of the gene which extends for at least 130-base pairs beyond the gcvP transcription terminator [2].
These genes are named gcvT, gcvH and gcvP, respectively [3].
The presence of a potential promoter preceding gcvT and a typical rho-independent terminator sequence following gcvP indicated that the three genes constitute a single operon [3].

References

Characterization of the Escherichia coli gcv operon. Stauffer, L.T., Fogarty, S.J., Stauffer, G.V. Gene (1994) [Pubmed]
A genomic polymorphism located downstream of the gcvP gene of Escherichia coli that correlates with ecological niche. Turner, S.J., Lewis, G.D., Bellamy, A.R. Mol. Ecol. (1997) [Pubmed]
Cloning and nucleotide sequence of the gcv operon encoding the Escherichia coli glycine-cleavage system. Okamura-Ikeda, K., Ohmura, Y., Fujiwara, K., Motokawa, Y. Eur. J. Biochem. (1993) [Pubmed]

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