Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

aspA - aspartate ammonia-lyase

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK4133, JW4099

Takagi, J.S. et al., Shi, W. et al.

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Disease relevance of aspA

The aspA gene of Escherichia coli W which encodes aspartase was cloned into the plasmid vector pBR322 [1].

High impact information on aspA

The nucleotide sequences of aspA and its flanking regions were determined [1].
Potential promoter and terminator sequences for aspA were also found in the determined sequence [1].
The structure of L-aspartate ammonia-lyase from Escherichia coli [2].

Associations of aspA with chemical compounds

The X-ray crystal structure of l-aspartate ammonia-lyase has been determined to 2.8 A resolution [2].

References

Cloning and nucleotide sequence of the aspartase gene of Escherichia coli W. Takagi, J.S., Ida, N., Tokushige, M., Sakamoto, H., Shimura, Y. Nucleic Acids Res. (1985) [Pubmed]
The structure of L-aspartate ammonia-lyase from Escherichia coli. Shi, W., Dunbar, J., Jayasekera, M.M., Viola, R.E., Farber, G.K. Biochemistry (1997) [Pubmed]

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