Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

CP - COAT PROTEIN

African cassava mosaic virus

Hong, Y. et al., Fondong, V.N. et al., Kumar P, P. et al., Padidam, M. et al.

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Disease relevance of CP

Its coat protein (CP) sequence is highly homologous to that of Indian cassava mosaic virus (90%) [1].
Based on the comparisons at the levels of both CP gene nucleotide and CP-deduced amino acid sequences with other geminiviruses, SqLCV-C is confirmed to be distinct from the American squash leaf curl virus (SqLCV-E) [2].

High impact information on CP

The sub-cellular localization of the betaC1 protein has been compared with that of the CP in yeast cells using a genetic system for detection of protein nuclear import and export [3].

Analytical, diagnostic and therapeutic context of CP

The nature of the viruses present was determined by using the PCR with primers specific for the coat protein (CP) genes of African cassava mosaic virus (ACMV) and East African cassava mosaic virus (EACMV) [4].

References

Tomato leaf curl geminivirus from India has a bipartite genome and coat protein is not essential for infectivity. Padidam, M., Beachy, R.N., Fauquet, C.M. J. Gen. Virol. (1995) [Pubmed]
Chinese squash leaf curl virus: a new whitefly-transmitted geminivirus. Hong, Y., Wang, X., Tian, B., Cai, J. Sci. China, Ser. B, Chem. Life Sci. Earth Sci. (1995) [Pubmed]
Protein-protein interactions and nuclear trafficking of coat protein and betaC1 protein associated with Bhendi yellow vein mosaic disease. Kumar P, P., Usha, R., Zrachya, A., Levy, Y., Spanov, H., Gafni, Y. Virus Res. (2006) [Pubmed]
Evidence of synergism between African cassava mosaic virus and a new double-recombinant geminivirus infecting cassava in Cameroon. Fondong, V.N., Pita, J.S., Rey, M.E., de Kochko, A., Beachy, R.N., Fauquet, C.M. J. Gen. Virol. (2000) [Pubmed]

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