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MeSH Review

Orbital Diseases

 
 
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Disease relevance of Orbital Diseases

  • CONCLUSIONS: In six patients with WG and active inflammatory orbital disease, orbital socket contracture occurred during the treatment course with systemic immunosuppressive medications [1].
  • Although first reported in the investigation of orbital disease in 1979, it is only in the past 1 to 2 years that CDI has become established as a tool in the assessment of vascular disease of the eye and orbit [2].
 

High impact information on Orbital Diseases

  • TBII or TSI titres did not correlate with thyroidal or orbital disease duration, nor with TPO antibody levels [3].
  • Coronal computed tomography in orbital disease [4].
  • During the first two years with the 160 x 160 matrix EMI scanner 144 consecutive patients referred with suspicion of orbital disease were subjected to 190 computed tomography (CT) examinations [5].
  • These observations may in part explain the lack of CSA effectiveness in human orbital diseases that respond to corticosteroids [6].

References

  1. Orbital socket contracture: a complication of inflammatory orbital disease in patients with Wegener's granulomatosis. Talar-Williams, C., Sneller, M.C., Langford, C.A., Smith, J.A., Cox, T.A., Robinson, M.R. The British journal of ophthalmology. (2005) [Pubmed]
  2. Color Doppler imaging of the ocular and orbital blood vessels. Aburn, N.S., Sergott, R.C. Current opinion in ophthalmology. (1993) [Pubmed]
  3. Association of thyrotrophin receptor antibodies with the clinical features of Graves' ophthalmopathy. Gerding, M.N., van der Meer, J.W., Broenink, M., Bakker, O., Wiersinga, W.M., Prummel, M.F. Clin. Endocrinol. (Oxf) (2000) [Pubmed]
  4. Coronal computed tomography in orbital disease. Takahashi, M., Tamakawa, Y. Journal of computer assisted tomography. (1977) [Pubmed]
  5. Computed tomography of orbital lesions. A radiological study of 144 cases. Gyldensted, C., Lester, J., Fledelius, H. Neuroradiology. (1977) [Pubmed]
  6. Orbital fibroblast interleukin-6 gene expression and immunomodulation. Burnstine, M.A., Elner, S.G., Strieter, R.M., Kunkel, S.L., Elner, V.M. Ophthalmic plastic and reconstructive surgery. (1999) [Pubmed]
 
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